Registration Dossier
Registration Dossier
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EC number: 944-090-8 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- other: Expert assessment
- Adequacy of study:
- key study
- Study period:
- January 31, 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: An assessment was performed based on the composition of the substance and information on an analogue substance.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- An assessment was performed based on the composition of the substance and information on an analogue substance.
- GLP compliance:
- no
- Type of method:
- other: An assessment was performed based on the composition of the substance and information on an analogue substance.
- Key result
- Water solubility:
- > 500 g/L
- Conc. based on:
- test mat.
- Remarks on result:
- other: An assessment was performed based on the composition of the substance and information on an analogue substance.
- Conclusions:
- The salt present in reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) has a water solubility of >500 g/L (>50 %).
- Executive summary:
Water solubility testing of a salt analogous to that present in Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) showed it to have a solubility of > 500 g L-1. It is reasonable to expect that the salt present in Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) would exhibit a similar degree of solubility.
The morpholine in Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) that is not present as part of the salt, is expected to exhibit a very high water solubility and it will most likely be fully miscible.
Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) contains a very significant proportion of water (typically around 40% w/w) and the organic constituents are completely dissolved within it. Addition of the substance to water in order to test its solubility could be considered an aqueous dilution rather than dissolution.
Reference
Description of key information
The salt present in reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) has a water solubility of >500 g/L (>50%).
Key value for chemical safety assessment
- Water solubility:
- 500 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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