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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-05-18 to 2017-07-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
adopted 27 July 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
30 May 2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Key result
Decomposition:
yes
Decomp. temp.:
>= 160 °C
Remarks on result:
not determinable
Remarks:
Substance decomposes

A preliminary thermogravimetric measurement was performed over a temperature range from room temperature to approx. 600 °C.

Three steps were registered with maxima at 88 °C, 187 °C resp. 451 °C. A total mass loss of 46.7 % at the final temperature could be observed (mass change in the range until 110 °C: 0.9 %; mass change in the range from 110 to 280 °C: 3.2 %; mass change in the range from 280 to 600 °C: 42.1 %). Mass loss due to purging: 0.5%.

The DSC measurements were performed twice in the temperature range from 20 - 400 °C. To determine a possible boiling point more precisely a crucible lid with a hole of 50 um diameter was used in the measurements to prevent evaporation.

No sharp endothermic peak indicating a melting point could be observed. ln the range of approx. 35 °C there was an indication for a glass transition.

Upon further heating the DSC-curve showed no endothermic peak. The course of the DSC-curve indicated decomposition starting at approx. 160 °C: Reweighing after the measurement showed that the sample had lost 6.7 %/ 7.1 % of its mass. After the first as well as after the second run the residue looked dark-brown discoloured and molten.

Conclusions:
The present study was performed according to OECD Test Guideline 103 (adopted 27 July, 1995) in order to determine the boiling point of Compimide 183. A thermogravimetric measurement and subsequently a differential scanning calorimetry (DSC) was performed. In the course of the thermogravimetric curve three steps were registered with maxima at 88 °C, 187 °C resp. 451 °C. A total mass loss of 46.7 % at the final temperature could be observed (mass change in the range until 110 °C: 0.9 %; mass change in the range from 110 to 280 °C: 3.2 %; mass change in the range from 280 to 600 °C: 42.1 %). Mass loss due to purging: 0.5%. During the DSC no sharp endothermic peak indicating a melting point could be observed. In the range of approx. 35 °C there was an indication for a glass transition. Upon further heating the DSC-curve showed no endothermic peak. The course of the DSC-curve indicated decomposition starting at approx. 160 °C: Reweighing after the measurement showed that the sample had lost 6.7 %/ 7.1 % of its mass. Thus, Compimide 183 is considered to decompose but exhibits no melting or boiling point.

Description of key information

- study conducted according to OECD 103 (adopted 27 July, 1995), thermogravimetric measurement and differential scanning calorimetry, no melting or boiling point, at > 160°C the substance decomposes

Key value for chemical safety assessment

Additional information

The present study was performed according to OECD Test Guideline 103 (adopted 27 July, 1995) in order to determine the boiling point of Compimide 183. A thermogravimetric measurement and subsequently a differential scanning calorimetry (DSC) was performed. In the course of the thermogravimetric curve three steps were registered with maxima at 88 °C, 187 °C resp. 451 °C. A total mass loss of 46.7 % at the final temperature could be observed (mass change in the range until 110 °C: 0.9 %; mass change in the range from 110 to 280 °C: 3.2 %; mass change in the range from 280 to 600 °C: 42.1 %). Mass loss due to purging: 0.5%. During the DSC no sharp endothermic peak indicating a melting point could be observed. In the range of approx. 35 °C there was an indication for a glass transition. Upon further heating the DSC-curve showed no endothermic peak. The course of the DSC-curve indicated decomposition starting at approx. 160 °C: Reweighing after the measurement showed that the sample had lost 6.7 %/ 7.1 % of its mass. Thus, Compimide 183 is considered to decompose but exhibits no melting or boiling point.