Registration Dossier
Registration Dossier
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EC number: 271-807-5 | CAS number: 68608-88-8 This substance is identified by SDA Substance Name: C11-C13 branched alkyl benzene sulfonic acid and SDA Reporting Number: 25-096-00.
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A group of 10 male and 10 female guinea pigs were used to determine the potential of the analog substance benzenesulfonic acid, 4 -C10 -13 -sec-alkyl derivs. to be sensitising to skin. The animals were first given an intradermal induction of 0.05% of test substance in corn oil. One week later, they were given a dermal induction of 5% test substance in corn oil. A group of 5 male and 5 female guinea pigs were used as controls. These animals were treated in a similar fashion with vehicle only. Two weeks after the dermal induction, a challenge was performed via dermal exposure to 2.5% test substance in corn oil. The control group was exposed as well. The animals were exposed for 24 hrs. Skin irritation readings were made at 24 and 48 hrs after the end of exposure. No positive responses were seen in either the test or control group. The test substance is not sensitising to skin.
Migrated from Short description of key information:
A guinea pig sensitization study was conducted to determine whether the substance was sensitizing. Results indicate that it is not a skin sensitizer.
Justification for classification or non-classification
No sensitizing reactions were observed in a guinea pig study on the analog substance
benzenesulfonic acid, 4 -C10 -13 -sec-alkyl derivs.
Therefore the substance does not need to be classified as a skin sensitizer.
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