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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Studies were conducted to evaluate the skin and eye irriation potential of the source substance, Benzenesulfonic acid, 4-C10-13-sec-alkyl derivs EC 287-494-3, CAS 85536-14-7. Which is strucutrally similar to the target substance, with differences in the branching of the alkyl side chain.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Studies were conducted to evaluate the skin and eye irriation potential of the analogue substance benzenesulfonic acid, 4 -C10 -13 -sec-alkyl derivs. For skin, the shaved backs of three male and three female rabbits were exposed for 4 hours to 0.5 ml of the test substance and observed for up to 14 days. Significant reddening was observed throughout at least day 9. Swelling was perceptible throughout and appeared to become more noticeable with time. Bloody wounds and scar formation were observed through at least observation day 9. Therefore the test substance is considered highly irritating to the skin of rabbits.

For eyes, the eyes of six rabbits were treated with the test substance and observed for six days. Results indicate that the substance was moderately irritating but because of the intensity of the necrosis formation the study was stopped at day 6.

Effects on skin irritation/corrosion: highly irritating

Effects on eye irritation: moderately irritating

Justification for classification or non-classification