Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Tests were conducted to compare the acute toxicity of sulfonic acid branched material (ABS) versus Linear (LAS). Results indicate they are comparable.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
520 mg/kg bw

Additional information

Tests were conducted to compare the acute oral toxicity of ABS and LAS. Groups of 3 male and 3 female rats were administered various doses of ABS or LAS. The animals were observed for 14 days for survival, behaviour, and appearance. In addition, body weights were taken on days 0, 7, and 14. The LD50 for ABS was 520 mg/kg, and the LD50 for LAS was 650 mg/kg. The LD50s for LAS and ABS were not statistically different. This demonstrates that LAS is a suitable analog for ABS regarding toxicity.

Justification for classification or non-classification

The substance is classified as Category 4, H302 under the CLP regulation.