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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1994-09-22 till 1994-11-15
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
In this method, the substance (solids must be pulverized) is dissolved in water at a temperature somewhat above the test temperature. When saturation is achieved the mixture is cooled and kept at the test temperature, stirring as long as necessary to reach equilibrium. Alternatively, the measurement can be performed directly at the test temperature, if it is assured by appropriate sampling that the saturation equilibrium is reached. Subsequently, the mass concentration of the substance in the aqueous solution, which must not contain any undissolved particles, is determined by a suitable analytical method.
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
405 mg/L
Temp.:
20 °C
pH:
10
Details on results:
Flask 1: 400 mg/L and pH 10.1;
Flask 2: 413 mg/L and pH 10.0;
Flask 3: 401 mg/L and pH 10.0
Mean: 405 mg/L and pH 10.0
Test temperature: 20 °C +/- 0.5 °C
Conclusions:
The water solubility of dibenzylamine was determined with Flask method according to EU Method A.6 (Water Solubility). The measurement showed a water solubility of 405 mg/L at a pH value of 10.0 and a test temperature of 20 °C +/- 0.5 °C.
Executive summary:

The water solubility of dibenzylamine was determined with Flask method according to EU Method A.6 (Water Solubility). The measurement showed a water solubility of 405 mg/L at a pH value of 10.0 and a test temperature of 20 °C +/- 0.5 °C.

Endpoint:
water solubility
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Principles of method if other than guideline:
no data
GLP compliance:
no
Type of method:
other: Calculation
Water solubility:
782 mg/L
Temp.:
25 °C
Remarks on result:
other: pH value was not reported

Description of key information

The water solubility of dibenzylamine was determined with Flask method according to EU Method A.6 (Key 1, Bayer AG, 1994).

The measurement showed a water solubility of 405 mg/L at a pH value of 10.0 and a test temperature of 20 °C +/- 0.5 °C.

Key value for chemical safety assessment

Water solubility:
405 mg/L
at the temperature of:
20 °C

Additional information

According to Meylan, 1996 (WoE, Key 2), the water solubility of dibenzylamine is 782 mg/L at 25°C.