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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption, other
Remarks:
QSAR
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2018-01-08
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
please refer to 'Attached justification'
Guideline:
other: ECHA Guidance R.6
Principles of method if other than guideline:
- Software tool(s) used including version: KOCWIN v2.00
- Model(s) used: EPIWIN v4.11
- Model description: see field 'Attached justification'
- Justification of QSAR prediction: see field 'Attached justification'
Key result
Type:
log Koc
Value:
2.38 dimensionless
Remarks on result:
other: MCI method
Key result
Type:
Koc
Value:
239.7 L/kg
Remarks on result:
other: MCI method
Conclusions:
The Koc of magnesium metaborate was predicted with KOCWIN v2.00, which is implemented in EPIWIN v4.11. The predicted Koc is 240 L/kg bw. However, this prediction does not fall within the applicability domain of this model, since the query substance is inorganic.
Executive summary:

The Koc of magnesium metaborate was predicted with KOCWIN v2.00, which is implemented in EPIWIN v4.11. The predicted Koc is 240 L/kg bw. However, this prediction does not fall within the applicability domain of this model, since the query substance is inorganic.

Description of key information

The Koc of magnesium metaborate was predicted with KOCWIN v2.00, which is implemented in EPIWIN v4.11. The predicted Koc is 240 L/kg bw [LogKoc: 2.38].

However, this prediction does not fall within the applicability domain of this model, since the query substance is inorganic.

Key value for chemical safety assessment

Koc at 20 °C:
240

Additional information

Determination of the adsorption coefficient was not carried out using the HPLC screening method, designed to be compatible with Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001, as the active ingredient in the test item was an inorganic. The test guidelines state they are not applicable to inorganic substances. A QSAR prediction has been made to allow PNEC derivation using partition-equilibrium method.

[LogKoc: 2.38]