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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The toxic effects of the test item on the oxygen consumption rate of Pseudomonas putida after a short-term exposure of 30 min was determined in a study (BASF SE, 1998) according to DIN 38412, Part 27 (1992) under GLP conditions. After 30 min following toxicity values based on nominal concentrations were determined for the test substance (Purity = 80 %): The EC0 (NOEC) was determined to be 30 mg/L, the EC10 was determined to be 37 mg/L and the EC50 was determined to be 75 mg/L. The corresponding values based on nominal concentrations for the test item with purity of 100 % were determined to be after 30 min as following: The EC0 (NOEC) was determined to be 24 mg/L, the EC10 for the test substance was determined to be 29.6 mg/L and the EC50 was determined to be 60 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
60 mg/L
EC10 or NOEC for microorganisms:
29.6 mg/L

Additional information

The objective of this key study (BASF SE, 1998) according to DIN 38412, Part 27 (1992) was to determine the toxic effects of the test substance on the oxygen consumption rate Pseudomonas putida after a short-term exposure of 30 min, compared with the blank control under GLP conditions. The test was performed in nominal concentrations of 0 (blank control), 10, 30 and 100 mg/L. No concentrations were measured. No positive control was prepared. After 30 min following toxicity values based on nominal concentrations were determined for the test substance (Purity = 80 %): The EC0 (NOEC) was determined to be 30 mg/L, the EC10 was determined to be 37 mg/L and the EC50 was determined to be 75 mg/L. The corresponding values for the test item with purity of 100 % were determined to be after 30 min as following: The EC0 (NOEC) was determined to be 24 mg/L, the EC10 for the test substance was determined to be 29.6 mg/L and the EC50 was determined to be 60 mg/L. All valued were based on nominal concentrations.