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EC number: 607-813-5
CAS number: 25830-77-7
The negative control responses for opacity
and permeability were less than the upper limits of the laboratory
historical rangeindicating that the negative control did not
induce irritancy on the corneas.The meanin vitroirritancy
score of the positive control (20% (w/v) Imidazole) was 118 and within
two standard deviations of the current historical positive control mean.
It was therefore concluded that the test conditions were adequate and
that the test system functioned properly.
Phthaloyl-L-glutamic acid anhydride induced
serious eye damage through both endpoints, resulting in a mean in
vitro irritancy score of 108 after 240 minutes of treatment.
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