Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-338-6 | CAS number: 94-49-5
When tested up to and including 25%, Ethylene glycol dibenzoate did not elicit an SI ≥ 3 and was therefore not considered to be a skin sensitizer. It was established that the EC3 value exceeds 25%. The test substance is not classified for skin sensitising properties.
Results of the pre-screen test:
At a 25% test item concentration no signs of systemic toxicity were noted and no erythema was observed. At a 50% test item concentration hunched posture was noted for both animals on Days 2 and 3 and slight erythema was noted for one of the animals on Day 2.
Test item remnants were present on the dorsal surface of the ears of all animals (between Days 1 and 6), which did not hamper scoring of the skin reactions.
Variations in ear thickness during the observation period were less than 25% from Day 1 pre-dose values.
Based on the tolerability of the test item, the highest test item concentration selected for the main study was a 25% concentration.
Based on the outcome of the available study the substance is not classifed as a skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again