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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Reference
Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well conducted study, using Differential Scanning Calorimetry(DSC) , purity included.
Qualifier:
no guideline available
Principles of method if other than guideline:
Thermal analysis Differential Scanning Calorimetry(DSC)
GLP compliance:
no
Other quality assurance:
other: ISO 9001
Test substance stable:
yes
Remarks:
overall stability is dependent on solvent: heptane, chloroform and acetone tested
Transformation products:
not measured

Overview of Setaram and TAM tests on Laurox.

Solvent

concentration

apparatus

mode

T

Q

1000/T

ln Q

ΔH

file

 

(% w/w)

 

 

(°C)

(W/kg)

(T in K)

 

(J/kg)

U:Nuk091

 

 

 

 

 

 

 

 

 

 

Heptane PA

9.75

Set. C80

scan

80.0

7.426

2.831

2.005

76100

32

 

9.75

Set. C80

scan

65

1.22

2.957

0.199

76100

32

 

10.02

Set. C80

iso

54.3

0.43

3.054

-0.844

 

40

 

9.96

TAM

iso

25

0.0032

3.354

-5.745

 

35

 

 

 

 

 

 

 

 

 

 

Chloroform PA

9.88

Set. C80

scan

80.1

18.14

2.831

2.898

83800

36

 

9.88

Set. C80

scan

65

2.75

2.957

1.012

83800

36

 

9.92

Set. C80

iso

54.3

1.27

3.054

0.239

 

37

 

9.73

TAM

iso

25

0.0066

3.354

-5.021

 

39

 

 

 

 

 

 

 

 

 

 

Acetone PA

5.02

Set. C80

scan

80

11

2.832

2.398

40800

42

 

5.02

Set. C80

scan

65

1.76

2.957

0.565

40800

42

 

5.02

TAM

iso

25

0.0065

3.354

-5.036

 

41

Overview of kinetic results

Solvent

Concentration

(w/w)

Ea

(kJ/Mole)

Ln C

k0

(1/s)

Temp. range

(°C)

 

Heptane

Chloroform

Acetone

 

10

10

5

 

123.47

125.87

118.10

 

44.18

45.94

42.60

2.03*1014

1.07*1015

7.75*1013

 

25 – 80

25 - 80

25 - 80

Conclusions:
Thermal stability of Dilauroyl peroxide expressed as the time to reach a conversion of 1% at 20°C is:
5.7 days for Dilauroyl peroxide dissolved in heptane
2.9 days for Dilauroyl peroxide dissolved in chlororform
1.6 days for Dilauroyl peroxide dissolved in acetone
Executive summary:

The study was conducted to determine the stability of the substance in various solvents by Thermal analysis Differential Scanning Calorimetry(DSC) to assist with other toxicology and ecotoxicology studies.

Thermal stability expressed as the time to reach a conversion of 1% at 20°C is: 5.7 days for Dilauroyl peroxide dissolved in heptane 2.9 days for Dilauroyl peroxide dissolved in chlororform 1.6 days for Dilauroyl peroxide dissolved in acetone

Description of key information

Thermal stability of Dilauroyl peroxide expressed as the time to reach a conversion of 1% at 20°C is:

5.7 days for Dilauroyl peroxide dissolved in heptane

2.9 days for Dilauroyl peroxide dissolved in chlororform

1.6 days for Dilauroyl peroxide dissolved in acetone

Additional information

The study was conducted to determine the stability of the substance in various solvents by Thermal analysis Differential Scanning Calorimetry(DSC) to assist with other toxicology and ecotoxicology studies.