Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-326-3 | CAS number: 105-74-8
Specific investigations: other studies
Administrative data
Link to relevant study record(s)
Description of key information
IARC Monograph Volume 71 discusses the studies summarized under this section. and concluded that, "Lauroyl peroxide is not classifiable as to its carcinogenicity to humans (Group 3)."
Additional information
Early investigations summarized in this section evaluating the potential of initiation/promotion and tumor formation following skin painting and S.C. injection have been summarized by IARC in Monograph 71 as follows.
"Lauroyl peroxide was tested for carcinogenicity by subcutaneous administration in mice and rats and by skin application in mice. In one study in mice by subcutaneous administration, the evidence concerning a carcinogenic effect was inconclusive; in two other studies, no increase in tumour incidence was observed. Two studies in mice by skin application were inadequate for an evaluation of complete carcinogenicity; one study indicated that lauroyl peroxide has promoting activity in mouse skin (IARC, 1985)."
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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