Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

 Fish

Acute toxicity to fish was investigated in a reliable key study according to OECD 203 and in compliance with GLP (RCC, 2000, RL1). As the test item was highly insoluble in water, a limit test was performed with a supersaturated solution prepared at 100 mg/L test item and filtered through 1.2 µm glass wool filter. Test concentrations were analytically verified. During exposure, no adverse effect (mortality) or other symptoms of intoxication (sublethal efffects) was observed. In conclusion, the test item showed no sign of acute toxicity to zebrafish above the maximum water solubility of the test item.

Daphnia

Acute toxicity to aquatic invertebrates was investigated in a reliable key study according to OECD 202 and in compliance with GLP (RCC, 2000, RL1). As the test item was highly insoluble in water, a limit test was performed with a supersaturated solution prepared at 100 mg/L test item and filtered through 1.2 µm glass wool filter. Test concentrations were analytically verified. During exposure, no immobility or mortality was observed. No other symptoms of intoxication were observed (sublethal effects). In conclusion, the test item showed no sign of acute toxicity to Daphnia magna above the maximum water solubility of the test item.

Algae

Toxicity to algae was investigated in a reliable key study according to OECD 201 and in compliance with GLP (RCC, 2000, RL2). As the test item was highly insoluble in water, a limit test was performed with a supersaturated solution prepared at 100 mg/L test item and filtered through 1.2 μm glass wool filter. Test concentrations were analytically verified. During exposure, no adverse effect on the biomass production or growth rate was observed. In conclusion, the test item showed no sign of toxicity to algae above the maximum water solubility of the test item.

Microorganisms

Toxicity on the respiration of activated sludge was investigated in a reliable key study according to OECD 209 and in compliance with GLP (RCC, 2000, RL2). The test was performed with concentrations up to 1000 mg/L test item. During exposure, no negative effects on the respiration rate of the activated sludge was observed at any test concentrations. In conclusion, the test item showed no sign of toxicity to activated sludge microorganisms up to 1000 mg/L test item.

Additional information