Registration Dossier
Registration Dossier
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EC number: 206-033-9 | CAS number: 294-62-2
Endpoint summary
Administrative data
Description of key information
Additional information
According to a Mackay Level I model calculation the main target compartment for cyclododecane will be the atmosphere (84.4 %), followed by sediment (7.8 %) and soil (7.7 %). The calculated Henry’s law constant of 103000 Pa m3/mol at 20 °C indicates high volatility of cyclododecane from surface waters. With a calculated Koc of 6513 l/kg (PCKowWin v1.66), the sorption potential of cyclododecane to soil or sediment organic matter is expected to be high (Blume scale).
The QSAR calculated rate constant for the OH sensitized photodegradation of cyclododecane is approximately 1.70E-11 cm3/(molecule * s). At 500,000 OH radicals / cm3 (approximate 24-hour mean in central Europe) this corresponds to a half-life of 22.7 hours. Cyclododecane was found not readily biodegradable but biodegradation was confirmed. Atmospheric OH sensitized photodegradation and biodegradation are expected to be the predominant ways of removal from the environment while photolytical or hydrolytical degradation in surface water are expected to be of minor importance. The partition coefficient 1-octanol/water of cyclododecane is log Kow = 7.6 at 25 °C, indicating very potential for bioaccumulation, which was confirmed by experimental bioconcentration factors between 3690 and 18100.
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