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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-11-20 to 2010-02-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 59: Sieve analysis
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
sieving
Type of distribution:
mass based distribution
Mass median aerodynamic diameter:
1 197 µm
Percentile:
D10
Mean:
377 µm
Remarks on result:
other: St. dev. not determined
Key result
Percentile:
D50
Mean:
1 197 µm
Remarks on result:
other: St. dev. not determined
Percentile:
D90
Mean:
2 309 µm
Remarks on result:
other: St. dev. not determined

The particle size distribution determined by the sieving is shown in the following table:

Mesh size

Range of particle size

Fraction

Particle size Lower Limit

Fraction

Particle size Upper Limit

Siftings

µm

µm

g

µm

%

µm

%

3150

>3150

1.75

31500

1.79

>31500

100.00

2500

2500 -3150

4.58

2500

4.68

31500

98.21

2000

2000 -2500

9.04

2000

9.24

2500

93.53

1600

1600 -2000

13.69

1600

14.00

2000

84.28

1000

1000 -1600

29.52

1000

30.18

1600

70.29

710

710 -1000

17.73

710

18.13

1000

40.10

500

500 -710

8.52

500

8.71

710

21.97

0

0-500

12.97

0

13.26

500

13.26

Conclusions:
In conclusion, the median particle size D50 of the test item was determined to be 1197 µm.
Executive summary:

In a GLP study according to OECD 110 and CIPAC MT 59 the particle size distribution of succinic anhydride has been determined. The particle size distribution was performed by sieve analysis. The results are as follows:

D10 = 377 μm

D50 = 1197 μm

D90 = 2309 μm

Description of key information

In a GLP study according to OECD 110 and CIPAC MT 59 the particle size distribution of succinic anhydride has been determined. The particle size distribution was performed by sieve analysis. The results are as follows:

D10 = 377 μm

D50 = 1197 μm

D90 = 2309 μm

Additional information