1,8-dihydroxy-4-nitro-5-(phenylamino)anthraquinone

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental starting date: 11/11/2016 - Experimental completion date: 12/12/2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Code number of the test material as used in the study report: FAT 40278/D TE
- Source and lot/batch No.of test material: Lot. AT-PD16-493A1
- Appearance: Dark blue powder

Key result

Water solubility:

< 0.85 µg/L

Conc. based on:

test mat.

Temp.:

20 °C

Remarks on result:

other: pH not specified

Details on results:

- The preliminary visual experiments showed that the water solubility of the test item is below 10 mg/L.
- Flask-Method: Average for 3 experiments: <0.85 μg/L. The recovery of 96.3 % indicates a sufficient accuracy of the analytical method.

Preliminary Visual Estimation of the Water Solubility:

Amount of the test item in mg	Total volume in ml	Appearance of mixture
10	10	undissolved
	50	undissolved
	100	undissolved
	1000	undissolved

The preliminary visual experiments showed that the water solubility of the test item is below 10 mg/l.

Flask-Method

Experiment	A	B	C	D(blank)
Amount of test item [mg]	1000	1000	1000	-
Stirring time at 30 °C [h]	24	48	72	72
Measured concentration [µg/l]	n.d. (< 0.85)	n.d. (< 0.85)	n.d. (< 0.85)	-
Dilution	undiluted	undiluted	undiluted	-
Water solubility [µg/l]	< 0.85	< 0.85	< 0.85	-

Average experiments A to C: < 0.85 μg/l

Conclusions:

The water solubility of FAT 40278/D was determined to be <0.85 μg/L.

Executive summary:

The water solubility of FAT 40278/D was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance at a temperature of 20 °C was determined to be <0.85 μg/L (without correction for the purity).

Description of key information

The water solubility of Disperse Blue 77 was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance at a temperature of 20 °C was determined to be < 0.85 μg/L (without correction for the purity).

Key value for chemical safety assessment

Water solubility:

0.85 µg/L

at the temperature of:

20 °C