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EC number: 202-401-8 | CAS number: 95-23-8
The test substance was tested for eye irritating properties according to OECD 405. Following these protocol 100 mg of the undiluted test substance were applied into the conjunctival sac of the left eye of 3 rabbits. The right eye remained untreated and served as a control. 24 h after instillation eyes were rinsed with physiol. saline. The eyes of the animals were examined at 1, 24, 48, and 72 h after test substance application. Mean scores (mean of 24, 48, 72h) were calculated for cornea, iris, conjunctivae redness, and conjunctivae chemosis for each animal.
Mean scores for all irritation parameters were below threshold values and were fully reversible within 72h.
Based on the findings in this test, the test substance is not eye irritating.
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