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Environmental fate & pathways

Hydrolysis

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Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report date:
2003

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Palladium(II) nitrate dihydrate
Cas Number:
32916-07-7
Molecular formula:
2NO3.Pd.2H2O
IUPAC Name:
Palladium(II) nitrate dihydrate
Details on test material:
40.1% palladium
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Details on sampling:
tests carried out at pH 4,7 and 9
Buffers:
pH 4: citrate - hydrochloric acid. pH 7: potassium dihydrogen phosphate - disodium hydrogen phosphate. pH 9: boric acid-potassium chloride-sodium hydroxide
Details on test conditions:
Details on test conditions: Substance dissolved in 2L of standard buffer solutions at 50°C +- 0.5°C
Duration of testopen allclose all
Duration:
5 d
pH:
4
Temp.:
50 °C
Initial conc. measured:
923 mg/L
Duration:
5 d
pH:
7
Temp.:
50 °C
Initial conc. measured:
224 mg/L
Duration:
5 d
pH:
9
Temp.:
50 °C
Initial conc. measured:
< 25 mg/L
Number of replicates:
2
Positive controls:
not specified
Negative controls:
not specified

Results and discussion

Preliminary study:
At pH 4 < 10% of the test item has been hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 is not required.

Applicant's summary and conclusion

Conclusions:
At pH 4 < 10% of the test item was hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 was not required.
Executive summary:

This is a GLP compliant, guideline study and is considered suitable for assessment. At pH 4 < 10% of the test item has been hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 is not required.