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EC number: 811-432-1 | CAS number: 78433-08-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Appearance/Physical state: White solid
Purity: >98%
Expiry date: 20 June 2017
Storage conditions: Room temperature in the dark - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- Pow
- Partition coefficient:
- > 3 160 000
- Temp.:
- 30 °C
- pH:
- 7
- Remarks on result:
- other:
- Remarks:
- Column temperature
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 6.5
- Temp.:
- 30 °C
- pH:
- 7
- Remarks on result:
- other:
- Remarks:
- Column temperature
- Details on results:
- The result from the preliminary test indicated that the HPLC method was suitable for determination of partition coefficient for this test item.
- Conclusions:
- The partition coefficient of the test item has been determined to be greater than 3.16 x 106, log10 Pow greater than 6.5.
Reference
Description of key information
In an OECD 117 study, under GLP conditions, the partition coefficient (Pow) of 2-Propenoic acid, 2‑[[(octadecylamino)carbonyl]oxy]ethyl ester is greater than 3.16 x 106, log10 Pow greater than 6.5 Envigo, 2016a).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.5
- at the temperature of:
- 30 °C
Additional information
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