Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
estimated by calculation
Adequacy of study:
key study
Study period:
2016
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: public database
Title:
No information
Year:
2016
Bibliographic source:
KOWIN v.1.68

Materials and methods

Principles of method if other than guideline:
KOWIN v.1.68
Type of method:
other: estimation
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Fatty acids C10-20, reaction product with diethylenetriamine
EC Number:
940-308-0
IUPAC Name:
Fatty acids C10-20, reaction product with diethylenetriamine

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
14
Remarks on result:
other: estimated value
Remarks:
Fatty acids, C10 -20 neo, reaction products with diethylenetriamine is an UVCB substance. The main component is a mixture of bis-amides, derived from the amidation reaction between Fatty acids, C10-20-neo-, and diethylenetriamine. Fatty acids, C10-20-neo- is a complex mixture of tertiary carboxylic acids, with C19 being the main component. Due to its complex composition, methods for the experimental measurement of partition coefficient octanol/water are technically not applicable. Furthermore the substance has surfactant properties, that complicate the measurement of Kow, and the resulting values are inaccurate and of limited utility for determining environmental fate and effects. On the basis of the water insolubility and its chemical nature, Kow value for the substance is expected to be high. Estimated Log Kow value for the main component (bis amide derived from the amidation reaction between C19 neo fatty acid and diethylenetriamine) is 14 (KOWIN v.1.68, September 2010; US EPA).

Applicant's summary and conclusion

Conclusions:
Fatty acids, C10 -20 neo, reaction products with diethylenetriamine is an UVCB substance. The main component is a mixture of bis-amides, derived from the amidation reaction between Fatty acids, C10-20-neo-, and diethylenetriamine. Fatty acids, C10-20-neo- is a complex mixture of tertiary carboxylic acids, with C19 being the main component.
Due to its complex composition, methods for the experimental measurement of partition coefficient octanol/water are technically not applicable. Furthermore the substance has surfactant properties, that complicate the measurement of Kow, and the resulting values are inaccurate and of limited utility for determining environmental fate and effects.
On the basis of the water insolubility and its chemical nature, Kow value for the substance is expected to be high. Estimated Log Kow value for the main component (bis amide derived from the amidation reaction between C19 neo fatty acid and diethylenetriamine) is 14 (KOWIN v.1.68, September 2010; US EPA).