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Description of key information

Key value for chemical safety assessment

Additional information

Experimental data on toxicokinetics of Y-15099 were not available. The toxicokinetic behaviour was assessed by expert judgement:


Y-15099 is predicted to be bioavailable.


General tissue accumulation is possible, but the potential is expected to be low.


Y-15099 has been identified as a potent skin sensitizer. This result confirms that the compound or its metabolites or hydrolysis products are capable of binding to proteins.


For the most metabolites biliary excretion is more likely than renal excretion.