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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Not readily biodegradable, dioctyltin oxide, OECD 301-F, EU Method C.4-D, Hanstveit 2003

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The ready biodegradability of the test material was assessed in a Manometric Respirometry test conducted in accordance with OECD guideline 301-F and EU Method C.4 -D and to GLP. Under the conditions of the study, the test material degraded approximately 2 % within 28 days of incubation with activated sludge. Two of the flasks performed with the test material gave negligible oxygen consumption, whilst the third gave 8 % within 28 days. All controls performed as part of the test demonstrated that the test system was operating correctly and the test material exhibited no toxic effect on the inoculum. All validity criteria of the guideline were met. Therefore, under the conditions of the study, the test material can be categorised as 'not readily biodegradable'.


As the study was performed on a read-across substance in the same category as the registered substance (di-n-octyltin oxide), it was assigned a reliability score of 2 (reliable with acceptable restrictions) in accordance with the criteria for assessing data quality as outlined in Klimisch (1997) and considered suitable for assessment as an accurate reflection of the test material.