Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
In accordance with point 8.8.1 of column 1 (Standard Information Required), Annex VIII of REACH (Regulation EC No. 1907/2006), an assessment of the toxicokinetic behaviour of the substance is performed to the extent that can be derived for the relevant available information. Testing for this endpoint is not required as an assessment of the basic toxicokinetic behaviour of the substance has been performed using the available physical-chemical and toxicological data available. Based on the available information, moderate absorption following oral administration is assumed, but it is estimated to be less absorbed following dermal exposure, and completely absorbed following inhalation. The substance is considered to be widely distributed within the body, hardly metabolised, and excreted mainly unchanged in the faeces. Any further testing would not provide any useful information that would assist in refining the risk assessment of this substance.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion