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Toxicological information

Endpoint summary

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Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Short description of key information:
Bacterial reverse mutation test (OECD 471, Eu method B.13/14): negative
In vitro mammalian cytogenetic study (OECD 483, EU method. B.10): negative
In vitro mammalian cell gene mutation test (OECD 476, EU method B.17): negative

Endpoint Conclusion:No adverse effect observed (negative)

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

"Resin 835 A" gave negative results in one bacterial gene mutation test, in one mammalian gene mutation test and in one mammalian cytogenetic study. All studies were performed under GLP and according to current guidelines. Therefore the test item was non-mutagenic in all three assays.


Short description of key information:
Bacterial reverse mutation test (OECD 471, Eu method B.13/14): negative
In vitro mammalian cytogenetic study (OECD 483, EU method. B.10): negative
In vitro mammalian cell gene mutation test (OECD 476, EU method B.17): negative

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

As there were negative results obtained in three in vitro genotoxicity tests "Resin 835 A" has not to be classified as mutagenic according to REGULATION (EC) No 1272/2008