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Administrative data

Description of key information

LD50/LC50 (4 -h) values are based on animal test data for acute toxicity.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
866 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Value:
14 700 mg/m³ air
Quality of whole database:
This value is for a 4-h LC50

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
560 mg/kg bw

Additional information

In an acute inhalation toxicity test, an 8h LC50 value was calculated as the geometric mean of the LC0 and LC100 value. Calculation using Haber's law, C*t =k (with 'n' is equal to 1), a 4h LC50 value of 14.7 mg/L was obtained. This is supported by another study, with an 8h LC0 value of 11 mg/L.

For acute oral toxicity as a worst case the lowest LD50 was selected.

Justification for classification or non-classification

The following classifications should be used: acute oral and inhalation toxicity GHS cat. 4, for acute dermal toxicity GHS cat. 3.