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EC number: 208-908-0 | CAS number: 546-67-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
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- Auto flammability
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
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- Dissociation constant
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- Additional physico-chemical information
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- Nanomaterial surface chemistry
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- Endpoint summary
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- Transport and distribution
- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
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- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
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- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Biotransformation and kinetics
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- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
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- Genetic toxicity
- Carcinogenicity
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- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
No guideline studies are available for the hydrolysis reaction of lead tetraacetate. One published reaction kinetics monitored by optical absorption spectroscopy indicates a completion after 8 minutes. Other studies indicate a much faster reaction (within seconds), but no reaction monitoring data have been published. A conservative half life time of < 8 minutes can be concluded.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 8 min
- at the temperature of:
- 20 °C
Additional information
An evaluation of hydrolysis reactions as published between 1851 and 1969 confirms the rapid hydrolysis of lead tetraacetate in contact with water. The reaction of lead acetate with ppm concentrations of water in different solvents at room temperature was monitored with optical absorption spectroscopy. After 8 minutes the reaction was complete as indicated by a plateau in the absorption curve. The reaction curve is not given, but a conservative half life time of 8 minutes is concluded.
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