Registration Dossier
Registration Dossier
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EC number: 203-466-5 | CAS number: 107-13-1
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
Description of key information
No data are available: a waiver is proposed for this endpoint. Bioaccumulation of acrylonitrile is not anticipated, given experimentally-derived values of 0-0.3 for the log Kow, and a bioconcentration factor (BCF) of 1.0 has been calculated from the known water solubility of acrylonitrile.
Key value for chemical safety assessment
- BCF (aquatic species):
- 1 dimensionless
Additional information
Physicochemical considerations and experimental evidence suggest that acrylonitrile is unlikely to bioaccumulate in exposed biota, and toxicity studies in mammalian species provide little evidence of cumulative toxicity in a range of species. Concentrations of acrylonitrile in biota are expected to be very low, and it is therefore concluded that the potential for secondary poisoning is very small.
Bioaccumulation of acrylonitrile is not anticipated, given experimentally-derived values of 0-0.3 for the log Kow, and a bioconcentration factor (BCF) of 1.0 has been calculated from the known water solubility of acrylonitrile.
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