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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The data overall suggest that acrylonitrile, while having an initial inhibitory effect on microorganisms, is of relatively low toxicity at concentrations below 100 mg/l.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
50 mg/L

Additional information

Results of biodegradation testing shows that acrylonitrile has an initial inhibitory effect on non-acclimated microorganisms, but following acclimation EC50s for microorganisms are generally in excess of 100 mg/l. The results of microbial toxicity tests and biodegradation studies on acrylonitrile indicate a potential effect on microorganisms in wastewater treatment plants, at least on start-up. The reported EC50s range from 1- >1,800 mg/l. Results with acclimated microbial populations and in simulation tests have indicated no inhibitory effect of acrylonitrile at levels as high as 200 mg/l, and a conservative estimate of 50 mg/l for a NOEC in such populations has been assumed (EU RAR 2004).