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EC number: 203-466-5 | CAS number: 107-13-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Additional ecotoxological information
Administrative data
- Endpoint:
- additional ecotoxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study is a public domain review of other public domain ecotoxicology studies. Information on the methods used for ecotoxicology testing are not presented in the paper and as such the reliability cannot be assessed fully.
Data source
Reference
- Reference Type:
- publication
- Title:
- Hazardous and noxious substances (HNS) in the marine environment: prioritizing HNS that pose major risk in a European context
- Author:
- Neuparth, T., Moreira, S., Santos, M., Reis-Henriques, M.
- Year:
- 2 011
- Bibliographic source:
- Marine Pollution Bulletin (62), 21-28
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Review of data available from other published studies.
- GLP compliance:
- no
- Type of study / information:
- The study aims to select and prioritize substances based on the risk they are likely to cause if spilled into the marine environment. In order to do this the study takes into account information on the volumes transported, reported incidents, physico-chemical properties and toxicity to marine organisms. Acrylonitrile is among the substances considered and data is included for toxicity to marine organisms.
Test material
- Reference substance name:
- Acrylonitrile
- EC Number:
- 203-466-5
- EC Name:
- Acrylonitrile
- Cas Number:
- 107-13-1
- Molecular formula:
- C3H3N
- IUPAC Name:
- prop-2-enenitrile
Constituent 1
Results and discussion
Any other information on results incl. tables
Table 1: Summary of ecotoxicological results for acrylonitrile
Test species |
Test type |
Aquatic medium |
Salinity (%)/ temperature (oC |
Age/size |
Effect concentration (mg/L) |
Effect measured |
Crustacea Artemia salina |
Acute |
Seawater |
NR/25 |
Nauplii |
14.34 (48h EC50) |
Survival |
Crustacea Crangon franciscorum |
Acute |
Seawater |
NR |
NR |
10-33 (24h LC50) |
Survival |
Fish Lagodon rhomboids |
Acute |
Seawater |
NR/ 13.7-20.4 |
NR |
24.5 (24h LC50) |
Survival |
Crustacea Daphnia magna |
Chronic |
Freshwater |
24 |
Neonates <24h |
1 (21 day LOEC) 0.5 ( 21 day NOEC) |
Reproduction |
Fish Cyprinus carpio |
Chronic |
Freshwater |
22 |
Embryo larva |
3.2 (7 day LOEC) 1.6 (7 day NOEC) |
Survival |
Applicant's summary and conclusion
- Conclusions:
- Acute and chronic values are presented for a number of freshwater and marine species. The lowest acute acute value was for Artemia salina with a 48-hour EC50 of 14.34 mg/L. The lowest chronic endpoint is that of Daphnia magna, with a 21-day NOEC of 0.5 mg/L.
- Executive summary:
A review was conducted of public domain data for the aquatic toxicity of acrylonitrile in order to assess the risk to the marine environment. Studies for both freshwater and marine species were presented.
The lowest acute acute value was for Artemia salina with a 48-hour EC50 of 14.34 mg/L. The lowest chronic endpoint is that of Daphnia magna, with a 21-day NOEC of 0.5 mg/L.
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