Registration Dossier

Administrative data

Description of key information

Not irritating to skin or eye.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin Irritation study was performed in accordance to OECD 404. Very slight erythema (grade 1) was observed in one animal only at the 1 hour observation period. All test sites appeared normal at 24 hours. Propoxylated glycerol mw 300 is not a skin irritant according EU criteria following a 4 hour occlusive exposure to rabbit skin. Classification: not irritating.

Eye Irritation study was performed in accordance to OECD 405. Conjuctival redness (grade 2) was observed in the eye of 2 rabbits at 1 hour post-instillation. Residual test material was observed around the treated eye of all rabbits 1 hour after treatment. All irritation fully reversed within 24 hours after dosing.

Propoxylated glycerol mw 300 was not an eye irritant according to EC criteria.

 

Justification for classification or non-classification

Findings of testing do not warrant classification according to EU GHS.