Registration Dossier
Registration Dossier
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EC number: 231-555-9 | CAS number: 7632-00-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
ICI (1985; cited in the OECD SIDS) reported a skin irritation study using rabbits. Some slight irritation was observed 1 hour after removal of sodium nitrite, but all signs had disappeared by the 1-day observation and the substance is not considered to be a skin irritant.
ICI (1985; cited in the OECD SIDS) reported an eye irritation study with rabbits. Conjunctival effects were seen in all animals and consisted of moderate redness, mild chemosis and severe discharge. All signs of irritation had disappeared by twelve days. No corneal effects were observed.
Justification for classification or non-classification
Classification concerning skin irritation is not warranted.
Classification proposal for eye irritation according to Regulation (EC) No. 1272/2008 Annex VI: Cat. 2A.
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