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REACH

Nickel bis(sulphamidate)

EC number: 237-396-1 | CAS number: 13770-89-3

Life Cycle description
Uses advised against

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Freshwater:

EC₅₀values are available for many species and range from 58.8 µg Ni/L forChlamydymonas species(Deleebeeck et al., 2009a) and the highest EC₅₀being 52300 µg Ni/L forAnacystis nidulans(Azeez and Banerjee, 1991).From the database of chronic nickel toxicity to freshwater algae, 58 individual NOEC’s are reported for 8 different algae species. NOEC/EC₁₀values range from 12.3 μg/l forScenedesmus accuminatus(Deleebeeck et al., 2009a) to 425 μg/l forPseudokirchneriella subcapitata(Deleebeeck et al., 2009b).

The following table indicates those NOEC or EC₁₀values of high quality that have been carried forward for the HC₅-& PNEC derivation:

Key Study (freshwater algae)	Selected values for the most sensitive endpoints used for derivation of the freshwater HC₅
Key Study (freshwater algae)	Species	Endpoint	Value (s) (µg/L)
Deleebeecket al., 2009b	Pseudokirchneriella subcapitata	EC₁₀	25.3-362
De Schamphelaere et al. (2006)	Pseudokirchneriella subcapitata	EC₁₀	63.0-425
Deleebeecket al., 2009a	Chlamydomonas sp.	EC₁₀	20.4-38.2
	Ankistrodesmus falcatus	EC₁₀	13.6-59.4
	Scenedesmus accuminatus	NOEC	12.3
	Chlorella	EC₁₀	42.0
	Desmodesmus spinosus	NOEC	22.5
	Pediastrum duplex	EC₁₀	20.1-28.2
	Coelastrum microporum	EC₁₀	41.2-51.8

Marine:

Two high quality EC₅₀values are available for species of marine algae, with the lowest EC₅₀being 456 µg Ni/L forChampia parvula(DeForest and Schlekat, 2013) and the highest EC₅₀being 4400 µg Ni/L forMacrocystic pyrifera(DeForest and Schlekat, 2013).From the database of chronic nickel toxicity to marine algae, EC₁₀values are reported for different species. EC₁₀values range from 97 μg Ni/L for growth of giant kelp (Macrocystis pyrifera) (DeForest and Schlekat, 2013) to 17891 μg Ni/L for growth of the dinoflagellate,Dunaliella tertiolecta(DeForest and Schlekat, 2013). The table below indicates the NOEC or EC₁₀values of high quality selected for derivation of HC₅and the marine aquatic PNEC:

Key Study (marine algae)	Selected values for the most sensitive endpoints used for derivation of the marine HC₅
Key Study (marine algae)	Species	Endpoint	Value (s) (µg/L)
DeForest and Schlekat, 2013	Macrocystis pyrifera	EC₁₀	96.7
DeForest and Schlekat, 2013	Champia parvula	EC₁₀	144
DeForest and Schlekat, 2013	Skelatonema costatum	EC₁₀	316.5 (geomean)
DeForest and Schlekat, 2013	Dunaliella tertiolecta	EC₁₀	17, 891

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