Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
237-396-1
CAS no.:
13770-89-3
Index number:
028-018-00-4
Molecular formula:
H3NO3S.1/2Ni
SMILES:
[Ni++].NS([O-])(=O)=O.NS([O-])(=O)=O
InChI:
InChI=1S/2H3NO3S.Ni/c2*1-5(2,3)4;/h2*(H3,1,2,3,4);/q;;+2/p-2
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
12
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP14) approved by the European Union, this substance may cause cancer by inhalation, may damage the unborn child, causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, is harmful if swallowed, is suspected of causing genetic defects, may cause an allergic skin reaction and may cause allergy or asthma symptoms or breathing difficulties if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may cause cancer, may damage fertility or the unborn child and is harmful if inhaled.

Breakdown of all 101 C&L notifications submitted to ECHA

Carc. 1A H350i Harmonised Classification
Repr. 1B H360D Harmonised Classification
STOT RE 1 H372 Harmonised Classification
Aquatic Acute 1 H400 Harmonised Classification
Aquatic Chronic 1 H410 Harmonised Classification
Muta. 2 H341 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Resp. Sens. 1 H334 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Acute Tox. 4 H332
Eye Dam. 1 H318
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (11.11% of REACH registrations).
  • M
Suspected to be Mutagenic (Harmonised C&L).
  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L).
  • R
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Toxic to Reproduction (11.11% of REACH registrations).
  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (11.11% of REACH registrations).
  • Sr
Officially recognised in the EU as Respiratory sensitising ( Harmonised C&L).
  • Sr
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Respiratory sensitising (11.11% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 8 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):
Some uses of this substance are restricted under Annex XVII of REACH.

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

This substance is used in articles, in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal), of articles where the substances are not intended to be released and where the conditions of use do not promote release and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery) and plastic (e.g. food packaging and storage, toys, mobile phones).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: metal surface treatment products and non-metal-surface treatment products.

This substance is used in the following activities or processes at workplace: transfer of chemicals at dedicated facilities, manual maintenance (cleaning and repair) of machinery, transfer of substance into small containers, laboratory work, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: metal surface treatment products.

This substance is used for the manufacture of: machinery and vehicles, fabricated metal products and electrical, electronic and optical equipment.

This substance is used in the following activities or processes at workplace: manual maintenance (cleaning and repair) of machinery, transfer of chemicals, mixing in open batch processes, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, treatment of articles by dipping and pouring and laboratory work.

Release to the environment of this substance can occur from industrial use: in the production of articles.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, transfer of substance into small containers and manual maintenance (cleaning and repair) of machinery.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • A.M.P.E.R.E. Deutschland GmbH, Emil-von-Behring Strasse 7-9 63128 DIETZENBACH Germany
  • A.M.P.E.R.E. INDUSTRIE, 5-7 Rue de Bretagne P.A. des Béthunes 95310 SAINT-OUEN-L'AUMONE VAL D'OISE France
  • BLUESTONE METALS & CHEMICALS EUROPE S.L., c/ Pascual y Genis 1 46002 Valencia Spain
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Str. 40 30926 Seelze Deutschland Germany
  • Königswarter & Ebell, Chemische Fabrik GmbH, Im Ennepetal 19-21 58135 Hagen Germany
  • TODINI AND CO. SPA, Corso Milano 46 B 20900 MONZA ITALIA Italy
  • TODINI BV, Kleine Pathoekeweg 82 B-8000 Brugge Belgium
  • Chemieservice Dr. Stoeber (P), Kefersteinstrasse 6 D-06110 Halle Germany
  • Only representative (No publishable name), null
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium

Substance names and other identifiers

Aeronikl 250
Other
Aeronikl 400
Other
Aeronikl 575
Other
Nickel bis(sulfamidate)
Cosmetic Products Regulation, Annex II - Prohibited Substances
nickel bis(sulfamidate); nickel sulfamate
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
nickel bis(sulfamidate);nickel sulfamate
C&L Inventory
Nickel bis(sulphamidate)
EC Inventory, REACH pre-registration
Nickel bis(sulphamidate)
REACH pre-registration, Other
Nickel sulfamate
Other
Nickel sulfamate (6CI,7CI)
Other
Nickel(II) sulfamate
Other
Sulfamic acid, nickel(2+) salt (2:1)
Other
bis(amidosíran) nikelnatý;nikélium-bis(sulfamát) (sk)
C&L Inventory
bis(solfamidato) di nichel;solfammato di nichel (it)
C&L Inventory
bis(sulfamidat) de nichel;sulfamat de nichel (ro)
C&L Inventory
bis(sulfamidate) de nickel;sulfamate de nickel (fr)
C&L Inventory
Bis(sulfamidato) de níquel;sulfamato de níquel (es)
C&L Inventory
Bis(sulfamidato) de níquel;sulfamato de níquel (pt)
C&L Inventory
bis(sulfamidian) niklu;amidosulfonian niklu (pl)
C&L Inventory
bis(sulfammidat) tan-nikil;sulfamat tan-nikil (mt)
C&L Inventory
Nickel-bis(sulfamidat);Nickelsulfamat (de)
C&L Inventory
nickelbis(sulfamidat);nickelsulfamat (sv)
C&L Inventory
nikelio disulfamidatas;nikelio sulfamatas (lt)
C&L Inventory
nikkel-bisz(szulfamidát);nikkel-szulfamát (hu)
C&L Inventory
nikkelbis(sulfamidaat);nikkelsulfamaat (et)
C&L Inventory
nikkelbis(sulfamidaat);nikkelsulfamaat (nl)
C&L Inventory
nikkelbis(sulfamidat);nikkelsulfamat (da)
C&L Inventory
Nikkelibis(sulfamidaatti);nikkelisulfamaatti (fi)
C&L Inventory
nikl-bis(sulfamidát);nikl-sulfamát (cs)
C&L Inventory
nikljev bis(sulfamidat);nikljev sulfamat (sl)
C&L Inventory
niklov bis(sulfamidat);niklov sulfamat (hr)
C&L Inventory
niķeļa bis(sulfamidāts);niķeļa sulfamāts (lv)
C&L Inventory
δις(σουλφαμιδικό) νικέλιο·σουλφαμικό νικέλιο (el)
C&L Inventory
никелов бис(сулфамидат);никелов сулфамат (bg)
C&L Inventory
Sulfamic acid, nickel(2+) salt (2:1)
Other
amidosulphuric acid
C&L Inventory
Nickel (2+) Disulfamate
C&L Inventory, Registration dossier
nickel bis(sulfamidate)
C&L Inventory
Nickel bis(sulphamidate)
C&L Inventory, Registration dossier
Nickel bis(sulphamidate)
C&L Inventory, Registration dossier
nickel sulfamate
C&L Inventory, Registration dossier
Nickel sulfamate
Registration dossier
nickel sulphamate
Registration dossier
Nickel sulphamate
Registration dossier
nickel(2+) disulfamate
C&L Inventory, Registration dossier, Other
nickel(2+);disulfamate
Other
Nickel sulfamate
Registration dossier
Nickel Sulphamate
Registration dossier
OMG Electronic Chemicals, LLC
Registration dossier
SULFAMATE NICKEL
Registration dossier
028-018-00-4
Index number
C&L Inventory
1333123-32-2
CAS number
Other
1333123-32-2
Deleted CAS number
Other
13770-89-3
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
2.25 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
2.25

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Non flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 328 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 90 2
Supporting study 156 2
Weight of evidence
Other 58 20
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 125 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 22
Supporting study 67 2 6
Weight of evidence
Other 28
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 83 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 38 14 2
Supporting study 9
Weight of evidence
Other 20
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 7.1 µg/L (2)
Intermittent releases (freshwater) 0 ng/L (2)
Marine water 8.6 µg/L (2)
Intermittent releases (marine water) 0 ng/L (2)
Sewage treatment plant (STP) 330 µg/L (2)
Sediment (freshwater) 109 mg/kg sediment dw (2)
Sediment (marine water) 109 mg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 29.9 mg/kg soil dw (2)
Hazard for Predators
Secondary poisoning 120 µg/kg food (2)

Short–term toxicity to fish

Study results
  • 259 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 15.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 130 2
Weight of evidence
Other 19 106
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 66 studies submitted
  • 12 studies processed
P/RResults
NOEC (32 days) 35 - 431 000 µg/L [22]
NOEC (30 days) 108.9 µg/L [2]
NOEC (8 days) 40 - 80 µg/L [4]
LOEC (32 days) 35 - 3 730 µg/L [22]
LOEC (30 days) 433.5 µg/L [2]

Type of Study provided
Studies with data
Key study 14
Supporting study 16 2
Weight of evidence
Other 22 12
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 355 studies submitted
  • 8 studies processed
P/RResults
LC50 (48 h) 13 - 276 µg/L [34]

Type of Study provided
Studies with data
Key study 8
Supporting study 184 24
Weight of evidence
Other 53 86
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 187 studies submitted
  • 48 studies processed
P/RResults
NOEC (8 months) 66 µg/L [2]
NOEC (4.233 months) 713 µg/L [2]
NOEC (56 days) 40 - 120 µg/L [4]
NOEC (42 days) 40 µg/L [4]
NOEC (36 days) 61 µg/L [2]

Type of Study provided
Studies with data
Key study 42 8
Supporting study 90
Weight of evidence
Other 35 12
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 187 studies submitted
  • 32 studies processed
P/RResults
EC50 (72 h) 40.7 - 1 430 µg/L [52]
IC50 (48 h) 456 - 4 400 µg/L [6]
NOEC (72 h) 3.5 - 5 476.8 µg/L [52]
NOEC (48 h) 10 - 110.5 µg/L [4]
LOEC (72 h) 6.2 - 11 551.3 µg/L [52]

Type of Study provided
Studies with data
Key study 10 22
Supporting study 58 4
Weight of evidence
Other 39 54
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 68 studies submitted
  • 2 studies processed
P/RResults
EC50 (7 days) 87 - 1 377 µg/L [12]
EC10 (7 days) 3.9 - 435.3 µg/L [12]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 20
Weight of evidence
Other 6 38
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 120 studies submitted
  • 2 studies processed
P/RResults
EC50 (30 min) 33 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 40
Weight of evidence
Other 6 72
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 108 studies submitted
  • 50 studies processed
P/RResults
NOEC (4 days) 900 µg/L [2]
LOEC (4 days) 1.8 mg/L [2]
EC10 (56 days) 762 - 1 625 mg/kg sediment dw [4]
EC10 (49 days) 210 - 339 mg/kg sediment dw [6]
EC10 (42 days) 160 - 3 307 mg/kg sediment dw [8]

Type of Study provided
Studies with data
Key study 24
Supporting study 18
Weight of evidence 34
Other 24 8
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 78 studies submitted
  • 12 studies processed
P/RResults
NOEC (42 days) 20 - 180 mg/kg soil dw [8]
NOEC (28 days) 100 - 700 mg/kg soil dw [6]
NOEC (21 days) 180 - 800 mg/kg soil dw [8]
LOEC (42 days) 320 mg/kg soil dw [2]
LOEC (28 days) 300 - 1 000 mg/kg soil dw [6]

Type of Study provided
Studies with data
Key study 12
Supporting study 20 4 2
Weight of evidence
Other 26 14
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 38 studies submitted
  • 6 studies processed
P/RResults
EC50 (28 days) 476 mg/kg soil dw [2]
LC50 (8.167 months) 8 351 mg/kg diet [2]
LC50 (28 days) 1 g/kg soil dw [2]
LOEC (28 days) 560 mg/kg soil dw [2]
NOEC (28 days) 36.4 - 1 140 mg/kg soil dw [4]

Type of Study provided
Studies with data
Key study 6
Supporting study 6
Weight of evidence
Other 16 10
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 455 studies submitted
  • 28 studies processed
P/RResults
NOEC (63 days) 29 - 355 mg/kg soil dw [8]
NOEC (60 days) 88 - 187 mg/kg soil dw [4]
NOEC (56 days) 17 - 69 mg/kg soil dw [6]
NOEC (40 days) 67 mg/kg soil dw [2]
NOEC (30 days) 13 - 187 mg/kg soil dw [8]

Type of Study provided
Studies with data
Key study 28
Supporting study 90
Weight of evidence
Other 149 188
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 76 studies submitted
  • 46 studies processed
P/RResults
NOEC (8.975 years) 86 mg/kg soil dw [4]
NOEC (1.381 years) 59 - 94 mg/kg soil dw [6]
NOEC (28 days) 41 mg/kg soil dw [2]
NOEC (7 days) 30 - 770 mg/kg soil dw [26]
EC10 (1.573 years) 295 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 46
Supporting study 10
Weight of evidence
Other 10 10
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 18 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study 4
Weight of evidence
Other 2 6
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 50 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) 104 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 50 µg/m³ -
Acute /short term: (DNEL) 1.6 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 440 ng/cm² sensitisation (skin)
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 60 ng/m³ developmental toxicity / teratogenicity
Acute /short term: (DNEL) 8.8 mg/m³ acute toxicity
Local Effects
Long-term: (DNEL) 60 ng/m³ repeated dose toxicity
Acute /short term: (DNEL) 100 µg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 11 µg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 370 µg/kg bw/day acute toxicity
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 1 3
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 6 studies submitted
  • 2 studies processed
P/RResults
LD50 1 098 mg/kg bw (rat) [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
inhalation
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 2 2
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2 2
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study 2
Weight of evidence
Other 2 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: respiratory
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2 4
Data waiving
no waivers
Study data: inhalation
  • 18 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 2
Supporting study 10 2
Weight of evidence
Other 2 2
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study
Weight of evidence 2
Other 2 2 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 4
Study data: in vivo
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other 2 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 4
Supporting study 2 4
Weight of evidence
Other 2 4
Data waiving
no waivers
Study data: developmental
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 4
Weight of evidence 2
Other 2 2
Data waiving
no waivers
Study data: other studies
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant

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