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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

The 21 day NOEC was reported as 0.16 mg/L.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
0.16 mg/L

Additional information

The study by Harlan Laboratories Ltd (2009) was selected as the key study as it is GLP compliant and follows standard guidelines. In addition all necessary details for evaluation of the study are provided in the report. This study reported 21 day EC50s for Daphnia magna were 0.45 mg/L (immobilisation) and 0.33 mg/L (reproduction). The 21 day NOEC was reported as 0.16 mg/L.