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EC number: 246-690-9 | CAS number: 25167-70-8
Eye irritation scores according to the Draize scheme
after 1 hour
after 24 hours
after 48 hours
after 72 hours
mean scores 24-72h
Eye irritation was assessed in a group of New Zealand white rabbits. 0.1 ml undiluted 2,4,4-trimethylpentene was instilled in the conjunctival sac and animals were observed for up to 8 days. Instillation caused slight initial pain in one animal but there was no initial pain response in the other 2 animals. Injection of the conjunctival blood vessels was present in each animal during the first 72 hours after instillation and iritis was present in one animal at the 1 hour assessment only. All signs of eye irritation had resolved by day 8. The mean values for ocular lesions at 24, 48 and 72 hours after instillation did not equal or exceed the EU limit values for classification of 2,4,4-trimethylpentene as "irritant to the eye".
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