Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
2008-10-15 to 2008-11-13
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Study according OECD Guideline and GLP, no deviations from Guideline, biodegradation equal/better than reference item sodium benzoate, toxicity control demonstrated no inhibitory effect of the test item. Read-across justification is given in the read-across document attached in IUCLID Section 13.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
Chemical Name: Sodium cocoyl glycinate

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, non-adapted
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
108 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution
Reference substance
Reference substance:
benzoic acid, sodium salt
Remarks:
at 20 mg/L

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
83 - 86
Sampling time:
28 d
Details on results:
Lag time was 1.5 d, Degradation time was 13.5 d, 10d window achieved (10% at day 1.5 and 60% at day 8)

BOD5 / COD results

Results with reference substance:
validity criteria was met based on degradation curve

Any other information on results incl. tables

In a toxicity test containing both the test item and the reference item >25% biodegradation was achieved within 14d and 84% after 28d. This means that the test item is not inhibitory.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Executive summary:

The biodegradability of the test item Hostapon SG (24,6% a.i. SCG) was investigated in an OECD 301B ready test with non-adapted inoculum over a period of 28d. The initial test item concentration was 108 mg/L. 83 -86% Biodegradation was achieved after 28d. The 10% level of degradation was reached after 1.5d and the 60% pass level after 8d. In a toxicity test with the reference substance sodium benzoate it was demonstrated that the test item in not inhibitory.

Based on the results given before the test item Hostapon SG is readily biodegradable fulfilling the 10d window.