Registration Dossier

Administrative data

Description of key information

In vivo studies for Skin and Eye irritation are present and indicate no skin irritation but moderately eye irritation.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

For Skin and Eye irritation, OECD-Guideline Studies are present which date to 1987. The studies are well documented and lead to valid conclusions on classification.


Justification for selection of skin irritation / corrosion endpoint:
Study well documented and according to OECD Guideline

Justification for selection of eye irritation endpoint:
- only one study available,
the study was evaluated by a regulatory organization
and was found to be sufficient.

Effects on eye irritation: moderately irritating

Justification for classification or non-classification

Benzotriazole is not irritant to the skin (with a score of 0 out of 8). According to CLP (EU-Regulation No 1272/2008) this score does not lead to a classification in category 1 or 2.

Benzotriazole is moderately irritant to the eye (with a score of 24 out of 100). The individual scores after 24 hours are >=1 which leads, according to CLP (EU-Regulation No 1272/2008), to a classification in category 2.