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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: testing method performed according to OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-6-chlorotoluene-3-sulphonic acid
EC Number:
201-837-6
EC Name:
4-amino-6-chlorotoluene-3-sulphonic acid
Cas Number:
88-51-7
Molecular formula:
C7H8ClNO3S
IUPAC Name:
2-amino-4-chloro-5-methylbenzene-1-sulfonic acid

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.97
Temp.:
23 °C
pH:
2.6
Remarks on result:
other: pH derived from water solubility test

Any other information on results incl. tables

Table 1: Results in detail

 determ. no.  stock solution [ml] n-octanol [ml] test substance conc. in n-octanol phase [mg/l] test substance conc. in water phase [mg/l]  log Pow 
 A1 5 10 15,84 33,20 -1,02
 A2 5 10 14,54 32,47 -1,05
 B1 10 10  18,04 34,33 -0,98
B2 10 10  17,85 34,39 0,98
C1 20 10  22,52 35,16 -0,89
C2 20 10  23,30 35,28 -0,88
mean  ---  ---  ---  ---  -0,97

Stock solution: 2475,0 mg/l

Conc. of filtered stock solution: 940,1 mg/l

 

Applicant's summary and conclusion

Conclusions:
Due to the partition coefficient n-octanol-water bioaccumulation is not expected.