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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 (48 h) > 100 mg/L for Daphnia magna (OECD 202)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
100 mg/L

Additional information

One study is available investigating the short-term effects of 2,2'-[ethane-1,2-diylbis(oxy)]bisethyl (CAS 111-21-7) diacetate to aquatic invertebrates (Vryenhoef, 2012). The study was performed according to OECD 202 under GLP conditions with the water flea Daphnia magna. A preliminary range-finding study did not result in any immobilisation up to 100 mg/L. Thus, a definitive limit test with a concentration of 100 mg/L was performed. No immobilisation of Daphnia magna was observed after 48 h. Thus, an EC50 (48 h) > 100 mg/L was derived. Analytical determination of the test concentrations at 0 and 48 h showed measured concentrations were 93% and 86% of nominal, respectively. Thus, the EC50 is based on the nominal concentration.