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Environmental fate & pathways

Hydrolysis

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Description of key information

Hydrolysis is not considered to be a relevant abiotic degradation process. A base-catalysed second-order hydrolysis rate constant of 0.491 L/(mol-sec) was estimated using a structure estimation method. This corresponds to half-lives of 163.4 days at pH 7 and 16.3 days at pH 8.

Key value for chemical safety assessment

Half-life for hydrolysis:
16.3 d
at the temperature of:
25 °C

Additional information

No experimental studies investigating the abiotic hydrolysis of 2,2'-[ethane-1,2-diylbis(oxy)]bisethyl diacetate (CAS 111-21-7) are available. However, in accordance with Regulation (EC) No. 1907/2006, Annex VIII, column 2, testing is not required since the substance can be regarded as readily biodegradable. In addition, supporting (Q)SAR estimations indicate that hydrolysis is a negligible pathway for the environmental fate of the substance:

SPARC v4.5

A base-catalysed second-order hydrolysis rate constant (Kb) of 0.491L/(mol-sec) at 25 degC was estimated using a structure estimation method.

This corresponds to half-lives of 163.4 days at pH 7 and 16.3 days at pH 8.

HYDROWIN v2.00

A base-catalysed second-order hydrolysis rate constant (Kb) of 0.5264 L/(mol-sec) at 25 degC was estimated using a structure estimation method.

This corresponds to half-lives of 152.4 days at pH 7 and 15.2 days at pH 8.