Registration Dossier
Registration Dossier
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EC number: 208-778-5 | CAS number: 541-41-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
Parent compound: No data available.
Hydrolysis product ethanol: In a respiration inhibition test with activated sludge following OECD TG 209, the 3 -h EC50 was determined to be > 1000 mg/L (Kleĉka et al., 1985).
The analogous hydrolysate of the methyl chloroformate (Methanol, HCl, CO2) was tested in a GLP study following OECD TG 209. The EC50 (30 min) was determined to be > 1000 mg/L, related to nominal concentrations of the parent compound (BASF AG, 1999).
Species |
Results |
Remarks |
Reference |
Activated sludge, domestic |
EC50 (3 h) > 1000 mg/L (nominal); OECD 209 respiration inhibition test |
Hydrolysis product ethanol; reliability: 2, key study |
Kleĉka et al., 1985 |
Pseudomonas putida |
EC3 (16 h) = 6500 mg/L(nominal); Bringmann-Kühn growth inhibition test |
Hydrolysis product ethanol; reliability: 2 |
OECD, 2005 |
Activated sludge, domestic |
EC50 (30 min) > 1000 mg/L (nominal), OECD TG 209 |
Hydrolysate (3 -d; Methanol, HCl, CO2); reliability: 1, key study |
BASF AG, 1999 |
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