Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.

REACH

Ethyl chloroformate

EC number: 208-778-5 | CAS number: 541-41-3

Life Cycle description
Uses advised against

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Hydrolysis product ethanol: With high probability not acutely harmful to aquatic algae.
Hydrolysis product HCl: Acutely very toxic to aquatic algae (pH dependent).

Key value for chemical safety assessment

Additional information

There are no data available concerning the parent compound. The hydrolysis product ethanol was tested in a growth inhibition test with Chlorella vulgaris. The resulting EC50 (96 h) was ca. 1000 mg/L and the NOEC was < 500 mg/L [OECD, 2005].

The hydrolysis product HCl showed acutely very toxic effects due to the low pH: 72 -h EC50 = 0.492 mg/L (OECD, 2002).

Species	Results	Remarks	Reference
Chlorella vulgaris	EC₅₀ (96 h) = ca. 1000 mg/L, NOEC (96 h) < 500 mg/L (nominal); algae growth inhibition test	Hydrolysis product ethanol; reliability: 2, key study	OECD, 2005
Skeletonema costatum (marine alga)	EC₅₀ (120 h) = 10943 mg/L, NOEC (120 h) = 3240 - 5400 mg/L (nominal); algae growth inhibition test	Hydrolysis product ethanol; reliability: 2, supporting study	OECD, 2005
Pseudokirchneriella subcapitata (formerly: Selenastrum capricornutum)	EC₅₀ (72 h) = 0.492 mg/L (acid equivalent to pH 5.3), NOEC (72 h) = 0.097 mg/L (acid equivalent to pH 6.0), with analytical monitoring, OECD TG 201	Hydrolysis product HCl; reliability: 2	OECD, 2002

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.