Registration Dossier
Registration Dossier
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EC number: 500-031-4 | CAS number: 9051-51-8 1 - 4.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
The substance showed no skin and eye irritating properties.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
In a dermal irritation/corrosion GLP study according to OECD 404, in which 3 female rabbits (Crl: KBL(NZW)BR) were exposed to Diethyleneglycol, propoxylated, no irritation was noted. There were no systemic intolerance reactions. According to classification criteria Diethyleneglycol, propoxylated is not an irritant to the skin.
In an eye irritation GLP study according to OECD 405, in which 3 male rabbits (New Zealand white Crl: KBL (NZW) SPF) were exposed to Diethyleneglycol, propoxylated, no irritation was noted. There were no reactions. According to classification criteria Diethyleneglycol, propoxylated is not an irritant to the eye.
Justification for classification or non-classification
Based on the results of a dermal irritation/corrosion and a eye irritation study, classification is not warranted in the EU.
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