Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from database
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
Danish Q(S)AR report, REACH guidance on QSARs R.6, May/July 2008

Test material

Constituent 1
Reference substance name:
1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters
EC Number:
270-487-4
EC Name:
1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters
Cas Number:
68442-70-6
Details on test material:
- Name of test material (as cited in study report): 1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters
- Analytical purity: no data

Results and discussion

Absorption in different matrices:
Dermal absorption of 1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters was predicted to be 0.00001 mg/cm2/event (very low).

Applicant's summary and conclusion