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Physical & Chemical properties

Vapour pressure

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Endpoint:
vapour pressure
Data waiving:
other justification
Justification for data waiving:
the study does not need to be conducted because the melting point is above 300°C
Endpoint:
vapour pressure
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Value published in Hazardous Substancea Data Bank (HSDB).
Qualifier:
no guideline followed
GLP compliance:
no
Type of method:
other: QSAR calculation
Temp.:
25 °C
Vapour pressure:
0.001 mm Hg
Conclusions:
The calculated value for the vapour pressure of creatine is 7.9E-4 mm Hg at 25 °C.
Executive summary:

No measured data are availbale regarding creatine (CAS 57-00-1) vapour pressure.

However, the Hazardous Substances Data Bank (HSDB) reports a peer-reviewed, calculated value of 7.9E-4 mm Hg at 15 °C (estimation program: US EPA, Estimation Programs Interface (EPI). ver. 3.11. U.S. EPA version for windows. Washington, DC: U.S. EPA (2003). Available from, as of Apr 27, 2005: http://www.epa.gov/oppt/exposure/pubs/episuitedl.htm)

Description of key information

In accordance with REACH Annex VII, column 2, the study does not need to be conducted as the melting point is above 300 °C.

Key value for chemical safety assessment

Vapour pressure:
0.105 Pa
at the temperature of:
25 °C

Additional information

No measured data are available regarding creatine (CAS 57-00-1) vapour pressure.

However, the Hazardous Substances Data Bank (HSDB) reports a peer-reviewed, calculated value of 7.9E-4 mm Hg at 15 °C (estimation program: US EPA, Estimation Programs Interface (EPI). ver. 3.11. U.S. EPA version for windows. Washington, DC: U.S. EPA (2003). Available from, as of Apr 27, 2005: http://www.epa.gov/oppt/exposure/pubs/episuitedl.htm)