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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1978
Report date:
1978

Materials and methods

Endpoint addressed:
skin irritation / corrosion
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Human patch test
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-(C8-18(even numbered) and C18 unsaturated acyl) derivs., hydroxides, inner salts
EC Number:
931-333-8
Cas Number:
147170-44-3
Molecular formula:
not applicable
IUPAC Name:
1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-(C8-18(even numbered) and C18 unsaturated acyl) derivs., hydroxides, inner salts
Constituent 2
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
dihydrogen oxide
Test material form:
solid - liquid: aqueous solution

Method

Ethical approval:
not specified
Details on study design:
Test item was diluted 1 : 10 in water.
Human patch test
Subjects: 40
Duration of treatment: 24 h application of patches soaked with the test item
Observation: 24, 48 and 72 h after treatment

Results and discussion

Results:
No irritation.
No one of the 40 subjects showed a skin reaction after treatment.

Applicant's summary and conclusion