Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.042 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.42 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.004 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
10 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.193 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.019 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.256 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Conclusion on classification

Degradation

Biodegradation: Not readily biodegradable: 41% (O2 consumption) after 28 d (OECD 301C)

Bioaccumulation

Log Kow: 1.28 (OECD 117)

Aquatic toxicity

96 h, LC50 (Oncorhynchus mykiss): 42 mg/L (nominal)

48 h, EC50 (Daphnia magna): > 100 mg/L (nominal)

72 h, ErC50 (Pseudokirchnerialla subcapitata): > 100 mg/L (nominal)

72 h, NOEC (Pseudokirchnerialla subcapitata):≥100 mg/L (nominal)

 

Classification according to CLP

Based on the data above, the acute aquatic toxicity L(E)C50 is > 1 mg/L. 2-(1-methylethoxy)ethyl acetate does not need to be classified and labeled as acute aquatic hazard according to the 2nd ATP of the Regulation (EC) No. 1272/2008 (CLP).

Valid chronic aquatic toxicity data are not available. Nevertheless, 2-(1-methylethoxy)ethyl acetate is considered to have a low potential for bioaccumulation but not to be rapidly degradable. Based on the LC50 (96 h) of 42 mg/L for Oncorhynchus mykiss, 2-(1-methylethoxy)ethyl acetate needs to be classified and labeled as environmental hazard Chronic Cat. 3 according to the 2nd ATP of the Regulation (EC) No. 1272/2008 (CLP).

Classification according to DSD

Based on the data above, 2-(1-methylethoxy)ethyl acetate is considered to be not rapidly degradable and has low potential for bioaccumulation. The acute aquatic toxicity LC50 (96 h) is 42 mg/L for Oncorhynchus mykiss. Thus, 2-(1-methylethoxy)ethyl acetate needs to be classified and labeled as environmental hazard R52/53 according to Directive 67/548/EEC.