2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)

GLP compliance:

no

Type of method:

shake-flask method to: flask method

Partition coefficient type:

octanol-water

Key result

Type:

Pow

Partition coefficient:

5.16

Temp.:

20 °C

Remarks on result:

other: The partition coefficient n-octanol/water of the test item at 20 °C, from the individual solubility in water and n-octanol, was determined to: log Pow = 5,16

Details on results:

Calculation of the partition coefficient log Pow from the individual solubility in water and n-octanol. By means of the flask method, the saturation concentration of the test item in n-octanol was determined to: 540 mg/l.
By means of the flask method, the saturation concentration of the test item in water was determined to: 3.7 μg/l

Conclusions:

The partition coefficient n-octanol/water of the test item at 20 °C, from the individual solubility in water and n-octanol, was determined to:
log Pow = 5.16

Executive summary:

n-octanol / water partition coefficient of the test substance was determined in a study conducted according to OECD Guideline 107 and EU Method A.8. The partition coefficient n-octanol/water of the test item at 20 °C, from the individual solubility in water and n-octanol, was determined to: log Pow = 5.16

Description of key information

The partition coefficient n-octanol/water of the test item at 20 °C  was determined to: log Pow = 5.16

Key value for chemical safety assessment

Log Kow (Log Pow):

5.16

at the temperature of:

20 °C

Additional information

n-octanol / water partition coefficient of the test substance was determined in a study conducted according to OECD Guideline 107 and EU Method A.8. The partition coefficient n-octanol/water of the test item at 20 °C, from the individual solubility in water and n-octanol, was determined to: log Pow = 5.16.