Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute data, based on international guidelines, are available for three trophic levels: Algae, Invertebrates and Fish and are summarized in the table below.


Among all the species tested, a toxic effect was found at the three trophic levels, and the most sensitive species was fish, (Oncorhynchus mykiss). The 96h-LC50 was determined to be 4.1 mg/L. A test was performed on this species following OECD guidelines, and conducted under GLP.


Two chronic studies are available, one on Daphnia magna to assess the toxicity of Amber Core on invertebrates and one on Pimephalese promelas to assess the toxicity of Amber Core on fish.

Long term toxicity information was located for Daphnia magna (LC50 > 1.4 mg/L and LC50 = 2.4 mg/L at 21 days, based on reproduction and immobilization, respectively). The NOEC for invertebrates was considered to be 1.4 mg/L.

In the long-term toxicity to fish Pimephales promelas, a 33 d NOEC of 0.22 mg/L was obtained. Test was performed on this species following OECD guidelines, and conducted under GLP.


EC50/LC50 (mg/L)

NOEC (mg/L)

Reference in IUCLID


Fresh water


Selenastrum capricornutum

Growth rate

72h: 12

Growth rate

72h: 1.5

6.1.5. 139504-68-0, Toxicity to aquatic algae and cyanobacteria, unknown author, 1995, K


72h: 5.6


Aquatic invertebrates

Daphnia magna

48h: 5.9

48h: 3.2

6.1.3. 139504-68-0, Short-term toxicity to aquatic invertebrates, Sunakawa, 1992, K


Oncorhynchus mykiss

96h: 4.1

96h: 1.8

6.1.1. 139504-68-0, Short-term toxicity to fish, Sunakawa, 1992, K


Aquatic invertebrates

Daphnia magna


21d: >1.4


21d: 1.4

6.1.4. 139504-68-0, Long-term toxicity to aquatic invertebrates, Sunakawa, 1995, K


21d: 2.4


21d: 1.4


Pimephales promelas


Length and weight

33d : 0.22

6.1.2. 139504-68-0, Long-term toxicity to fish, Goodband and Mullee, 2009, K


A study on the toxicity of Amber Core on microorganisms is also available. Amber Core had no significant inhibitory effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The EC50 of the test material could not therefore be calculated but these must be greater than 100 mg/L, the highest tested level.