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Short-term toxicity to aquatic invertebrates

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Description of key information

A key study evaluating the short-term toxicity of Amber Core (P-#620) to aquatic invertebrates (Daphnia magna) is available. The 48h-EC50 was determined to be 5.9 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
5.9 mg/L

Additional information

One key study according to the OECD Guideline 202 part I and EEC Directive 67/548 Annex V part C.2 (84/449/EEC) with GLP standards is available on the aquatic invertebrates (Daphnia magna). Groups of twenty, 1stinstar Daphnia were exposed for 48 hours to 9 concentrations of Amber Core (P-#620) dispersed in water: 0.10, 0.18, 0.32, 0.56, 1.0, 1.8, 3.2, 5.6 and 10 mg/L plus one control and one solvent control. The incidence of immobilisation was recorded for each test and control group at 24 hours and at 48 hours. The 48h-EC50 and 48h-NOEC were determined to be 5.9 mg/L (95% confidence limits: 5.3 – 6.7 mg/L) and 3.2 mg/L respectively. All results are expressed in terms of measured concentration. Measured concentrations ranged from 83 to 106% of nominal at 0 hours and 60 to 95% of nominal at 48 hours (average 87%).